Dr. Ajay K. Singh

Academic & Scientific Advisor

Continuous Flow Chemistry | API Synthesis | Reaction Automation

Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India

About

Dr. Ajay K. Singh is a researcher working in chemical synthesis, continuous-flow processes and the development of advanced chemical technologies. His research spans organic synthesis, catalytic processes, functional materials and applications relevant to pharmaceuticals, energy, water and sensors.

He obtained his Ph.D. in 2012 from the University of Gorakhpur, India. Following research fellowships at CSIR-CSMCRI, Bhavnagar, he completed postdoctoral research with Professor Dong-Pyo Kim at POSTECH, South Korea. He subsequently joined CSIR-IICT, Hyderabad, through the DST-INSPIRE Faculty programme and progressed through scientific roles.

Research Interests

Continuous Flow Chemistry Flow-based chemical synthesis and process development.

Pharmaceutical API Synthesis Efficient synthesis and process intensification for active pharmaceutical ingredients.

Electrochemical & Photochemical Synthesis Flow reactor platforms for electrochemical and light-driven transformations.

Reaction Automation Automated experimentation, reaction optimization and data-driven synthesis.

Catalysis & Advanced Materials Catalysts and functional materials for chemical transformations and energy-related applications.

Organic Synthesis Synthetic organic chemistry, hydrogenation and development of new synthetic methods.

Academic & Professional Background

Ph.D. in Chemistry — 2012

University of Gorakhpur, India.

Research Fellowships

Senior Research Fellowship and extension at CSIR-CSMCRI, Bhavnagar, India.

Postdoctoral Research

POSTECH, South Korea, working with Professor Dong-Pyo Kim.

CSIR-IICT, Hyderabad

Joined through the DST-INSPIRE Faculty programme and subsequently held scientific positions. His reported research activities include automation in API synthesis.

Selected Research Publications

The following publications illustrate research areas associated with continuous-flow synthesis, microreactors and process automation. This is a selected list, not a complete publication record.

Micro-total envelope system (μ-TES) with silicon nanowire separator for safe carcinogenic chemistry

Nature Communications, 2015.

Integrated carbon dioxide capture-fixation chemistry via interfacial ionic liquid catalyst in laminar gas/liquid flow

Nature Communications, 2017.

Micro-electro-flow reactor (μ-EFR) system for ultra-fast arene synthesis and manufacture of daclatasvir

Chemical Communications, 2019.

Integrated multi-step continuous flow synthesis of daclatasvir without intermediate purification and solvent exchange

Reaction Chemistry & Engineering, 2020.

Manual to Auto-Optimization Platform of Multistep Apixaban Synthesis

Organic Process Research & Development, 2025.

UV–visible Auto-Reactometry enabled parallel screening for accelerating chemical synthesis development with LLM

Chemical Engineering Journal, 2026.

Photo-Flow Sulfur Alkylation of Sulfenamides for Direct Access of the S-Methyl Sulfoximines

The Journal of Organic Chemistry, 2026.

Relevance to SmartChemSynth

Dr. Ajay K. Singh’s research interests in continuous-flow synthesis, electrochemical and photochemical processes, API synthesis and reaction automation align with SmartChemSynth’s focus on integrated flow reactors and intelligent chemistry solutions.